The twenty-second comfort zone rests on friendship. Not on family and not on colleagues — precisely on chosen people, to whom the person is bound by nothing obligatory.
This is important for those close to them to understand: not because family counts for less, but because strength reaches such a person from a different source. A friend who has invited them often carries more weight with them than a relative who has asked.
Hence the vulnerability. The twenty-second zone takes the break-up of a friendship harder than is usually considered normal, and takes a long time to recover.
The best state arrives when there are a few of one's own people nearby, and one sees them not for an occasion but simply because.